Research teams

In order to improve knowledge in the field of neuromuscular and skeletal diseases, collaborative projects have been set up thanks to a solid collaboration between clinical and research teams from the APHP, Inserm and Sorbonne University within the FHU MAMUTH.

Spinal surgery remains a very complex and complex procedure, given its link to the vital organs to generate movement and function via the nervous and vascular systems, and it requires digital innovations and the development of new operating theatre technologies. Robotics is also being used to treat the disabilities associated with an ageing population. The integration of surgical instruments equipped with sensors, real-time multimodal data processing algorithms and robotic control schemes incorporating this data is more than necessary to improve quality and personalise the pre-, intra- and post-operative phases for a better experience for both the patient and the surgical team.

This digital transformation of the operating theatre can only be achieved with the complementary expertise of academics and industry. This area of research is part of the remit of the GRC-33 Clinical Research Group “Robotics and Surgical Innovation” at Sorbonne University, the University Institute of Spinal Surgery (IUCR) and the BOPA “Augmented Operating Theatre” Chair at the APHP.

Georges Charpak Human Biomechanics Institute is a joint team of ARTS ET MÉTIERS Paris-Tech and the University of Paris XIII. It is located on the Paris campus of ARTS ET MÉTIERS Paris-Tech.

The institute provides an ideal forum for research between clinicians and engineers into human biomechanics, with a particular focus on understanding the mechanisms of damage to the neuro-musculo-skeletal system and contributing to the design and improvement of prevention, diagnosis and treatment methods.

The Myology Research Centre is a multi-disciplinary research centre focusing on muscle and its pathologies, bringing together international experts in this field. It is located at the heart of the Pitié-Salpêtrière Hospital Group and the Sorbonne University Faculty of Medicine. The Centre is a Joint Health Research Unit (UMRS 974) with two supervisory bodies:

  • Sorbonne University (SU)
  • and the Institut National de la Santé et de la Recherche Médicale (INSERM).

It also has a special partnership with the Association Institut de Myologie (AIM).

LIP6 is a computer science research laboratory dedicated to modelling and solving fundamental application-driven problems, as well as implementing and validating solutions through academic and industrial partnerships.

ISIR is under the joint supervision of Sorbonne University and the Centre National de la Recherche Scientifique (CNRS). The French National Institute for Health and Medical Research (Inserm) also supervises the AGATHE team’s medical research. ISIR brings together multidisciplinary teams that are helping to anticipate the profound changes that robots and artificial intelligence systems will bring to our societies, by working on the autonomy of machines and their ability to interact with human beings.

Collaboration with rare disease networks

Current research projects 

Pediatric Spine RegistryPediatric Spine FoundationR.VIALLERecruitment of all patients suffering from spinal and/or chest wall disorders, in order to monitor them throughout their care.In progress
LigaPCAPHPR. VIALLEStudy of the ankle ligamentoplasty process: towards new biomarkersIn progress
SpinalMeD-1SUR. VIALLEDesign and testing of a new medical device for metabolic monitoring of the spinal cord during surgery.In progress
Hôpitaux de
M. BACHYRetrospective study of the decision to amputate the foot for congenital malformation.In progress
APHPM. BACHYRetrospective comparative study of the morbidity of the donor area for grafting in the treatment of congenital syndactyly in children.In progress
VIAMSAPHPM. BACHYValidation of 2 video analysis and artificial intelligence techniques for analysing movement of the child’s upper limb in a healthy paediatric population aged between 6 and 18 years.In preparation
EOS et élastographiesInstitut de Biomécanique Humaine Georges CharpakC. VERGARILink between disc elastography and spine stiffness
(measured by bending radiography)
In progress
APHPR. VIALLENational Protocol for Diagnosis and Care (PNDS):
Early spinal deformities
PRIUM 2APHPF. DHOMBRESPrenatal in utero fetoscopic repair programme for sacral myelomeningocele and myelo-LDM
SUOGSUF. DHOMBRESSmart Ultrasound in Obstetrics & Gynecology dépistage des anomalies fœtalesIn progress
Cov-MumAPHPJ.M. JOUANNICMeasuring the emotional impact of separating patients who have given birth during the confinement periodCompleted
AUTONOMIASUB. RIOUA research centre for technological innovation on ageing, the aim of which is to promote research to combat dependency linked to illness, ageing or disability. R. VIALLE is in charge of developing the innovation axis for electric wheelchairs, exoskeletons and simulation-based training for surgeons.In progress
POOMAAPHPM. LorrotAcute non-severe osteomyelitis in children – Outpatient management strategy with oral antibiotic therapy compared with a standard strategy with conventional hospitalisation and intravenous antibiotic therapy: randomised open-label non-inferiority study with Bayesian and medico-economic analysesIn progress
IRM POPBAPHPM. BACHYDevelopment of the fibre tracking MRI imaging technique for mapping nerve lesions in brachial plexus injuries.In progress
APHPL. GuilbaudEvaluation of the benefit of a mesenchymal stromal cell patch in the antenatal treatment of myelomeningocele in the ewe foetus (Experimental study – AAP Filière Maladie Rare Neurosphinx)In progress
APHPL. GuilbaudHuman and Social Sciences and Foetal Surgery: In utero surgery for foetal myelomeningocele: decision-making mechanisms and the psychological impact of prenatal therapy.In progress
SUL. GuilbaudStudy of translation in the human foetusIn progress
APHPR. VIALLEIn vivo study of spinal cord elastography before and after filum section in paediatric patients with an attached cordIn progress